Yes you can use PDFs on your website, but you will violate one of the longest-lasting web design guidelines if you do. And you will very likely annoy your users. PDFs are created for the medium of print, not for screen presentation on the Internet.
Of course, you don’t take our word for it; read what Jakob Nielsen wrote more than ten years ago:
Users get lost inside PDF files, which are typically big, linear text blobs that are optimized for print and unpleasant to read and navigate online. PDF is good for printing, but that’s it. Don’t use it for online presentation. PDF: Unfit for Human Consumption